Now we will discuss the different subtypes of stomach cancer.
It may be broadly divided into two histopathological types, intestinal type, and diffuse type.
First, we will compare the demographics or the population distribution of the two different variants of the stomach cancer, that is, the intestinal and diffuse type.
As you can see in this figure, an intestinal variant is more commonly in elderly, whereas, diffuse type os more common in a young population.
Intestinal variant is more commonly seen in the males, whereas, diffuse variant is more common in the females.
Intestinal variant is common in endemic regions of Japan and south-east Asia, whereas, diffuse variant is more common in the developed low incidence countries.
To understand the location of these tumors and pathophysiology, first we have to know the normal anatomy of the stomach.
As you can see in this figure, the stomach lies in the upper part of the abdomen, called as epigastric region.
Gastroesophageal junction is the landmark where the esophagus joins the stomach. The most upper part of stomach is known as cardia. Below the cardia, liest the body of stomach.
The most distal part of the stomach, where it narrows down, is called as antrum.
And pylorus is the distance sphincter of the stomach, that controls the passage of stomach contents into the small intestine.
Now, after understanding the normal anatomy of the stomach, we will compare the distribution of the intestinal and the diffuse variant.
As you can see in this figure, the intestinal variant of stomach cancer is most commonly located either in the body or the pylorus.
Whereas the diffuse variant may be seen equally in any part of the stomach, that is, either cardia, body or pylorus. This are the type of stomach cancer.
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