Treatment of Metastatic Breast Cancer

Video Transcript:

Let’s move on to the treatment for metastatic breast cancer.

Metastatic disease constitutes for 5-10% of the cases of breast cancer.

This figure shows spread to both the lungs in form of multiple metastatic nodules.

And here, metastasis to the pleural covering of lungs has resulted in fluid collection, called as pleural effusion.

This figure shows spread to liver, in form of multiple nodular deposits.

And here cancer has spread to the adrenal gland. Similarly, the spread may occur to the brain, bones or other parts of the body.

The treatment options for metastatic breast cancer are chemotherapy, hormonal therapy for ER PR positive disease, and anti Her-2 therapy for Her-2 positive disease.

Radiotherapy or surgery may be added for palliation, i.e., reduction of symptoms, and bone redirected therapy may be given in presence of bone metastasis.

Remember cure is not the intent of giving treatment in metastatic breast cancer. It is mainly given to prolong the life, reduction of symptoms, and improvement of the quality of life.

Treatment for metastatic disease is decided based on the site of metastasis, previous treatments taken, ER, PR, HER-2 status, performance status of the patient and the comorbidities in the patient.

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