- Age: Older age men are generally at increased risk of developing prostate cancer. About 60% of all the incidence of prostate cancer is observed in men older than 65 years of age.
- Family history: Individuals with a history of prostate cancer in close relatives are considered to be at increased risk of developing prostate cancer.
- Genetic alterations: Some inherited genetic alterations have been reported to be associated with a high risk of prostate cancer, e.g., Lynch syndrome or hereditary non-polyposis colorectal cancer (HNPCC, generally caused by mutation in the MLH1 or MSH2 gene), mutations in RNASEL, MSR1, HOXB13, and BRCA2 genes, etc.
- Race/ethnicity: African-American and Caribbean men are generally at higher risk of developing and dying of prostate cancer.
- Overweight or obese males are at higher risk of developing an aggressive form of prostate cancer.
- Diet: It has been reported that a diet rich in red meat, fats, dairy foods, and calcium may increase the risk of prostate cancer, while an adequate consumption of vegetables and antioxidants such as vitamin E and selenium may reduce the risk of prostate cancer.
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To further understand the disease in a better way, have a look at the video below where CancerBro meets Mr. Poppy who has recently being diagnosed with prostate cancer. CancerBro asks Mr. Poppy several important questions related to his disease from early symptoms which lead him to contact an oncologist, to various other risk factors related to prostate cancer.